Alpha-Fetoprotein (AFP) Antibody

AFP (alpha-fetoprotein), a major plasma protein produced by the yolk sac and the liver during fetal life.Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma.However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology.The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4.Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin.The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.

Target	Alpha-Fetoprotein (AFP)
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Mouse
Recommended dilutions	ELISA: 1/10000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Purified recombinant fragment of human AFP expressed in E. coli.
Isotype	IgG2b
Form	Liquid
Purification	Unpurified ascites.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
GeneID	174 11576
Molecular Weight	69 kDa
Buffer	Ascitic fluid containing 0.03% sodium azide.
Concentration	Not determined.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Alpha-Fetoprotein (AFP)

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