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Alpha-Fetoprotein (AFP) Antibody

Catalogue No: abx000589
Price: £95.00
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Alpha-Fetoprotein (AFP) Antibody

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AFP Antibody is a Rabbit Polyclonal antibody against AFP. This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.

Target AFP
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Synthetic peptide. C term -peptide of human AFP.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UNSPSC Code 12352203
UniProt Primary AC P02771
Gene Symbol AFP
GeneID 174
Molecular Weight Calculated MW: 68 kDa
Observed MW: 65 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration 1.19 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Alpha-Fetoprotein (AFP) Antibody

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