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Alpha-Fetoprotein (AFP) Antibody
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Catalogue No: abx000589
Price:
£120.00
(Size: 20 µl)
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AFP Antibody is a Rabbit Polyclonal antibody against AFP. This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.
Research Articles on AFP
| Target | AFP |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Synthetic peptide. C term -peptide of human AFP. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P02771 (UniProt, ExPASy) |
| UniProt Secondary AC | B2RBU3 |
| UniProt Entry Name | FETA_HUMAN |
| Gene Symbol | AFP |
| GeneID | 174 |
| KEGG | hsa:174 |
| String | 9606.ENSP00000379138 |
| Molecular Weight | Calculated MW: 68 kDa Observed MW: 65 kDa |
| Buffer | PBS, pH 7.3, 0.02% sodium azide, 50% glycerol. |
| Concentration | 1.19 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |
