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AG 1478
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Catalogue No: abx076728
Price:
US$348.00
(Size: 5 mg)
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Datasheet
AG 1478 is a small molecule. AG 1478 is a potent and selective inhibitor of EGFR. It does so by reducing EGF-stimulated DNA synthesis (seen in rat fibroblasts) and blocking EGF-dependent src-family kinase activation and p21/Cip 1/WAF1 induction (seen in A431 cells). AG 1478 is cell-permeable and active in vivo.
Research Articles on AG 1478
| Target | AG 1478 |
| Origin | Synthetic |
| Form | Solid |
| Purity | > 98% (HPLC) |
| Storage | Store at -20 °C. |
| Molecular Weight | 315.8 g/mol |
| Molecular Formula | C16H14ClN3O2 |
| CAS Number | 153436-53-4 |
| SMILES | COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)Cl)OC |
| Availability | Shipped within 5-12 working days. |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
