Adenosylhomocysteinase (AHCY) Antibody

AHCY Antibody is a Rabbit Polyclonal antibody against AHCY. S-adenosylhomocysteine hydrolase belongs to the adenosylhomocysteinase family. It catalyzes the reversible hydrolysis of S-adenosylhomocysteine (AdoHcy) to adenosine (Ado) and L-homocysteine (Hcy). Thus, it regulates the intracellular S-adenosylhomocysteine (SAH) concentration thought to be important for transmethylation reactions. Deficiency in this protein is one of the different causes of hypermethioninemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Target	Adenosylhomocysteinase (AHCY)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 253-432 of human AHCY.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P23526 (UniProt, ExPASy)
UniProt Secondary AC	A8K307, B3KUN3, E1P5P2, F5H737, Q96A36
UniProt Entry Name	SAHH_HUMAN
Gene Symbol	AHCY
GeneID	191
NCBI Accession	NP_000678.1
KEGG	hsa:191
String	9606.ENSP00000217426
Molecular Weight	Calculated MW: 48 kDa Observed MW: 45 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Adenosylhomocysteinase (AHCY)

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