Aryl Hydrocarbon Receptor (AHR) Antibody

AHR Antibody is a Rabbit Polyclonal antibody against AHR. The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that has been largely regarded as a mediator of xenobiotic metabolism [PMID:18483242]. It plays a part role in physiologic activities, including attenuation of the acute phase response, cytokine signaling, T helper (TH)17 immune cell differentiation, modulation of NF-κB activity, and regulation of hormonal signaling [PMID:20423157,18540824]. It also mediates transcription factor sequestering away from a gene promoter or tethering of the AhR to a transcription factor on a promoter.

Target	Aryl Hydrocarbon Receptor (AHR)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/1000 - 1/5000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 619-848 of human AHR.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P35869 (UniProt, ExPASy)
UniProt Secondary AC	A4D130, Q13728, Q13803, Q13804
UniProt Entry Name	AHR_HUMAN
Gene Symbol	AHR
GeneID	196
NCBI Accession	NP_001612.1
KEGG	hsa:196
String	9606.ENSP00000242057
Molecular Weight	Calculated MW: 96 kDa Observed MW: 100 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Aryl Hydrocarbon Receptor (AHR)

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