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Aryl Hydrocarbon Receptor (AHR) Antibody
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Catalogue No: abx001244
Price:
£120.00
(Size: 20 µl)
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AHR Antibody is a Rabbit Polyclonal antibody against AHR. The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that has been largely regarded as a mediator of xenobiotic metabolism [PMID:18483242]. It plays a part role in physiologic activities, including attenuation of the acute phase response, cytokine signaling, T helper (TH)17 immune cell differentiation, modulation of NF-κB activity, and regulation of hormonal signaling [PMID:20423157,18540824]. It also mediates transcription factor sequestering away from a gene promoter or tethering of the AhR to a transcription factor on a promoter.
Research Articles on AHR
| Target | AHR |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/200 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant protein of human AHR. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P35869 (UniProt, ExPASy) |
| UniProt Secondary AC | A4D130, Q13728, Q13803, Q13804 |
| UniProt Entry Name | AHR_HUMAN |
| Gene Symbol | AHR |
| GeneID | 196 |
| KEGG | hsa:196 |
| String | 9606.ENSP00000242057 |
| Molecular Weight | Calculated MW: 96 kDa Observed MW: 115 kDa |
| Buffer | PBS, pH 7.3, 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.5 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |
