Aurora Kinase A (AURKA) Antibody
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Catalogue No: abx033751
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US$326.25
(Size: 80 µl)
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Datasheet SDS
Aurora A (AIK/AURKA) plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal. Aurora A is viewed as a potential target for anticancer drug treatment.
Research Articles on Aurora Kinase A (AURKA)
| Target | Aurora Kinase A (AURKA) |
| Research Area | Enzymes and Kinases |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 90-120 amino acids from the N-terminal region of human AIK. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | O14965 (UniProt, ExPASy) |
| UniProt Secondary AC | E1P5F9, O60445, O75873, Q9BQD6, Q9UPG5 |
| UniProt Entry Name | AURKA_HUMAN |
| Gene Symbol | AURKA |
| GeneID | 6790 |
| OMIM | 603072 |
| HGNC | 11393 |
| KEGG | hsa:6790 |
| Ensembl | ENSG00000087586 |
| String | 9606.ENSP00000216911 |
| Molecular Weight | Calculated MW: 45.8 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Concentration | 1.8 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |