Aldose Reductase (AKR1B1) Antibody

Catalogue No: abx001414
Price: £120.00
(Size: 20 µl)
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Aldose Reductase (AKR1B1) Antibody

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AKR1B1 Antibody is a Rabbit Polyclonal antibody against AKR1B1. This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database. [provided by RefSeq, Feb 2009].

Target Aldose Reductase (AKR1B1)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-316 of human AKR1B1.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P15121 (UniProt, ExPASy)
UniProt Secondary AC B2R8N3, Q5U031, Q6FGA4, Q6ICP2, Q9BS21, Q9UCI9
UniProt Entry Name ALDR_HUMAN
Gene Symbol AKR1B1
GeneID 231
OMIM 103880
NCBI Accession NP_001619.1
HGNC 381
KEGG hsa:231
Ensembl ENSG00000085662
String 9606.ENSP00000285930
Enzyme Commission Number EC 1.1.1.21
Molecular Weight Calculated MW: 35 kDa
Observed MW: 36 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration 1.03 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Aldose Reductase (AKR1B1) Antibody

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