Aldo-Keto Reductase Family 1 Member C3 (AKR1C3) Antibody

AKR1C3 Antibody is a Rabbit Polyclonal antibody against AKR1C3. AKR1C3(Aldo-keto reductase family 1 member C3) is also named as DDH1, HSD17B5, KIAA0119, PGFS and belongsi to AKR1C family.In humans, at least four AKR1C isoforms exist: AKR1C1, AKR1C2, AKR1C3, AKR1C4 and AKR1C3 shares >86% sequence identity with these three highly related human AKRs(PMID:18574251). It catalyzes the conversion of aldehydes and ketones to alcohols and androgen, estrogen, PG, xenobiotics metabolism. The rat kidney possesses a dimeric form of 75 kDa(PMID:18574251).

Target	Aldo-Keto Reductase Family 1 Member C3 (AKR1C3)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	WB, IF/ICC, IP
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IF/ICC: 1/50 - 1/200, IP: 0.5-4 µg/200-400 µg whole cell extracts. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-323 of human AKR1C3.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P42330 (UniProt, ExPASy)
UniProt Entry Name	AK1C3_HUMAN
Gene Symbol	AKR1C3
GeneID	8644
NCBI Accession	NP_003730.4
KEGG	hsa:8644
String	9606.ENSP00000369927
Molecular Weight	Calculated MW: 37 kDa Observed MW: 37 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Aldo-Keto Reductase Family 1 Member C3 (AKR1C3)

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