RAC-Beta Serine/Threonine-Protein Kinase Phospho-Ser474 (AKT2 pS474) Antibody
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Catalogue No: abx031949
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US$326.25
(Size: 80 µl)
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Datasheet SDS
AKT2 is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. Furthermore, AKT2 was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression of AKT2 contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. AKT2 is a general protein kinase capable of phophorylating several known proteins.
Research Articles on RAC-Beta Serine/Threonine-Protein Kinase Phospho-Ser474 (AKT2 pS474)
| Target | RAC-Beta Serine/Threonine-Protein Kinase Phospho-Ser474 (AKT2 pS474) |
| Clonality | Polyclonal |
| Target Modification | Ser474 |
| Modification | Phosphorylation |
| Reactivity | Human |
| Tested Applications | ELISA, DB |
| Host | Rabbit |
| Recommended dilutions | DB: 1/500. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S474 of human AKT2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by two-step phosphospecific peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P31751 (UniProt, ExPASy) |
| UniProt Secondary AC | B2RBD8, Q05BV0, Q0VAN0, Q0VAN1, Q68GC0 |
| UniProt Entry Name | AKT2_HUMAN |
| KEGG | hsa:208 |
| String | 9606.ENSP00000375892 |
| Molecular Weight | Calculated MW: 55.8 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |