Aldehyde Dehydrogenase, Mitochondrial (ALDH2) Antibody
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Catalogue No: abx027972
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US$326.25
(Size: 80 µl)
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Datasheet SDS
This product is currently in development. The lead time for this product may be several months. Please contact us at [email protected] for an updated lead time before purchasing this product. ALDH2 belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Asians have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Asians than among Caucasians could be related to the absence of the mitochondrial isozyme.
Research Articles on Aldehyde Dehydrogenase, Mitochondrial (ALDH2)
| Target | Aldehyde Dehydrogenase, Mitochondrial (ALDH2) |
| Research Area | Enzymes and Kinases, Metabolism, Hepatology |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | WB, IHC, FCM |
| Host | Rabbit |
| Recommended dilutions | Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Human ALDH2 recombinant protein. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P05091 (UniProt, ExPASy) |
| UniProt Secondary AC | B4DW54, E7EUE5, Q03639, Q6IB13, Q6IV71 |
| UniProt Entry Name | ALDH2_HUMAN |
| NCBI Accession | NP_000681.2 NP_001191818.1 |
| KEGG | hsa:217 |
| String | 9606.ENSP00000261733 |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |