Aldehyde Dehydrogenase, Mitochondrial (ALDH2) Antibody

Catalogue No: abx001138
Price: £120.00
(Size: 20 µl)
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ALDH2 Antibody is a Rabbit Polyclonal antibody against ALDH2. Acetaldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism. It mediates NADP+-dependent oxidation of aldehydes into acids during detoxification of alcohol-derived acetaldehyde; lipid peroxidation; and metabolism of corticosteroids, biogenic amines and neurotransmitters. Genetic variation in ALDH2 is responsible for individual differences in responses to drinking alcohol. Thus, the absence of this enzyme is linked to alcohol intolerance and a reduced risk for alcoholism-related liver disease.

Target ALDH2
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-380 of human ALDH2.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P05091 (UniProt, ExPASy)
UniProt Secondary AC B4DW54, E7EUE5, Q03639, Q6IB13, Q6IV71
UniProt Entry Name ALDH2_HUMAN
Gene Symbol ALDH2
GeneID 217
KEGG hsa:217
String 9606.ENSP00000261733
Molecular Weight Calculated MW: 50 kDa, 56 kDa
Observed MW: 54 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration 7.93 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on ALDH2

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