Aldehyde Dehydrogenase 4 Family, Member A1 (ALDH4A1) Antibody

ALDH4A1 Antibody is a Rabbit Polyclonal antibody against ALDH4A1. This protein belongs to the aldehyde dehydrogenase family of proteins. This enzyme is a mitochondrial matrix NAD-dependent dehydrogenase which catalyzes the second step of the proline degradation pathway, converting pyrroline-5-carboxylate to glutamate. Deficiency of this enzyme is associated with type II hyperprolinemia, an autosomal recessive disorder characterized by accumulation of delta-1-pyrroline-5-carboxylate (P5C) and proline. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Target	Aldehyde Dehydrogenase 4 Family, Member A1 (ALDH4A1)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/2000 - 1/7000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 354-563 of human ALDH4A1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P30038 (UniProt, ExPASy)
UniProt Entry Name	AL4A1_HUMAN
Gene Symbol	ALDH4A1
GeneID	8659
NCBI Accession	NP_003739.2
KEGG	hsa:8659
String	9606.ENSP00000364490
Molecular Weight	Calculated MW: 62 kDa Observed MW: 62 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Aldehyde Dehydrogenase 4 Family, Member A1 (ALDH4A1)

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