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Methylmalonate-Semialdehyde Dehydrogenase [acylating], Mitochondrial (ALDH6A1) Antibody

Catalogue No: abx002356
Price: £120.00
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Methylmalonate-Semialdehyde Dehydrogenase [acylating], Mitochondrial (ALDH6A1) Antibody

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ALDH6A1 Antibody is a Rabbit Polyclonal antibody against ALDH6A1. This gene encodes a member of the aldehyde dehydrogenase protein family. The encoded protein is a mitochondrial methylmalonate semialdehyde dehydrogenase that plays a role in the valine and pyrimidine catabolic pathways. This protein catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids. Alternate splicing results in multiple transcript variants.

Target ALDH6A1
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human ALDH6A1.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q02252 (UniProt, ExPASy)
UniProt Secondary AC B2R609, B4DFS8, J3KNU8, Q9UKM8
UniProt Entry Name MMSA_HUMAN
Gene Symbol ALDH6A1
GeneID 4329
KEGG hsa:4329
String 9606.ENSP00000450436
Molecular Weight Calculated MW: 56 kDa, 57 kDa
Observed MW: 58 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Methylmalonate-Semialdehyde Dehydrogenase [acylating], Mitochondrial (ALDH6A1) Antibody

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