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Fructose-Bisphosphate Aldolase A (ALDOA) Antibody
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Catalogue No: abx001056
Price:
US$217.50
(Size: 20 µl)
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ALDOA Antibody is a Rabbit Polyclonal antibody against ALDOA. The protein encoded by this gene, Aldolase A (fructose-bisphosphate aldolase), is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia. Alternative splicing and alternative promoter usage results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 3 and 10.
Research Articles on Fructose-Bisphosphate Aldolase A (ALDOA)
| Target | Fructose-Bisphosphate Aldolase A (ALDOA) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/2000, IF/ICC: 1/20 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant protein corresponding to ALDOA. The exact sequence is proprietary. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P04075 (UniProt, ExPASy) |
| UniProt Secondary AC | B4DXI7, Q6FH76, Q6FI10, Q96B15, Q9BWD9, Q9UCN2 |
| UniProt Entry Name | ALDOA_HUMAN |
| Gene Symbol | ALDOA |
| GeneID | 226 |
| OMIM | 103850 |
| NCBI Accession | NP_908930.1 |
| HGNC | 414 |
| KEGG | hsa:226 |
| Ensembl | ENSG00000149925 |
| String | 9606.ENSP00000378669 |
| Molecular Weight | Calculated MW: 39 kDa Observed MW: 43 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |