Fructose-Bisphosphate Aldolase A (ALDOA) Antibody

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Catalogue No: abx001056
Price: US$203.00
(Size: 20 µl)

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Datasheet SDS
ALDOA Antibody is a Rabbit Polyclonal antibody against ALDOA. The protein encoded by this gene, Aldolase A (fructose-bisphosphate aldolase), is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia. Alternative splicing and alternative promoter usage results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 3 and 10.

Target Fructose-Bisphosphate Aldolase A (ALDOA)
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IF/ICC: 1/20 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-348 of human ALDOA.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P04075 (UniProt, ExPASy)
UniProt Secondary AC B4DXI7, Q6FH76, Q6FI10, Q96B15, Q9BWD9, Q9UCN2
UniProt Entry Name ALDOA_HUMAN
Gene Symbol ALDOA
GeneID 226
OMIM 103850
NCBI Accession NP_908930.1
HGNC 414
KEGG hsa:226
Ensembl ENSG00000149925
String 9606.ENSP00000378669
Molecular Weight Calculated MW: 39 kDa
Observed MW: 43 kDa
Buffer PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration > 0.2 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Fructose-Bisphosphate Aldolase A (ALDOA)


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