Fructose Bisphosphate Aldolase B (ALDOB) Antibody

ALDOB Antibody is a Rabbit Polyclonal antibody against ALDOB. Fructose-1,6-bisphosphate aldolase (EC 4.1.2.13) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A, B, and C are distinct proteins, the products of a family of related 'housekeeping' genes exhibiting developmentally regulated expression of the different isozymes. The developing embryo produces aldolase A, which is produced in even greater amounts in adult muscle where it can be as much as 5% of total cellular protein. In adult liver, kidney and intestine, aldolase A expression is repressed and aldolase B is produced. In brain and other nervous tissue, aldolase A and C are expressed about equally. There is a high degree of homology between aldolase A and C. Defects in ALDOB cause hereditary fructose intolerance.

Target	Fructose Bisphosphate Aldolase B (ALDOB)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human ALDOB.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P05062 (UniProt, ExPASy)
UniProt Secondary AC	Q13741, Q13742, Q5T7D6
UniProt Entry Name	ALDOB_HUMAN
Gene Symbol	ALDOB
GeneID	229
NCBI Accession	NP_000026.2
KEGG	hsa:229
String	9606.ENSP00000363988
Molecular Weight	Calculated MW: 39 kDa Observed MW: 40 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Fructose Bisphosphate Aldolase B (ALDOB)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue