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Fructose Bisphosphate Aldolase B (ALDOB) Antibody

Catalogue No: abx002683
Price: £120.00
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Fructose Bisphosphate Aldolase B (ALDOB) Antibody

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ALDOB Antibody is a Rabbit Polyclonal antibody against ALDOB. Fructose-1,6-bisphosphate aldolase (EC 4.1.2.13) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A, B, and C are distinct proteins, the products of a family of related 'housekeeping' genes exhibiting developmentally regulated expression of the different isozymes. The developing embryo produces aldolase A, which is produced in even greater amounts in adult muscle where it can be as much as 5% of total cellular protein. In adult liver, kidney and intestine, aldolase A expression is repressed and aldolase B is produced. In brain and other nervous tissue, aldolase A and C are expressed about equally. There is a high degree of homology between aldolase A and C. Defects in ALDOB cause hereditary fructose intolerance.

Target ALDOB
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/1000 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human ALDOB.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P05062 (UniProt, ExPASy)
UniProt Secondary AC Q13741, Q13742, Q5T7D6
UniProt Entry Name ALDOB_HUMAN
Gene Symbol ALDOB
GeneID 229
KEGG hsa:229
String 9606.ENSP00000363988
Molecular Weight Calculated MW: 39 kDa
Observed MW: 39 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Fructose Bisphosphate Aldolase B (ALDOB) Antibody

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