Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP) Antibody
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Catalogue No: abx033750
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US$326.25
(Size: 80 µl)
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Datasheet SDS
ALOX5AP is a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation.
Research Articles on Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP)
| Target | Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 86-117 amino acids from the Central region of human ALOX5AP. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified Rabbit Polyclonal Antibody. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P20292 (UniProt, ExPASy) |
| UniProt Secondary AC | Q5VV04 |
| UniProt Entry Name | AL5AP_HUMAN |
| Gene Symbol | ALOX5AP |
| GeneID | 241 |
| KEGG | hsa:241 |
| String | 9606.ENSP00000479870 |
| Molecular Weight | Calculated MW: 18.2 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Rat, Cow, Pig, Sheep and Monkey ALOX5AP. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |