Alpha Fetoprotein (AFP) Antibody (HRP)

Alpha-Fetoprotein Antibody (HRP) is a Rabbit Polyclonal antibody conjugated to HRP against Alpha-Fetoprotein. α-fetoprotein is a major plasma protein produced by the yolk sac and the liver during fetal life. α-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of α-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the α-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. α-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of α-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.

Target	Alpha Fetoprotein (AFP)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA
Host	Rabbit
Recommended dilutions	Optimal dilutions/concentrations should be determined by the end user.
Conjugation	HRP
Immunogen	Recombinant human Alpha-fetoprotein (19-609AA).
Isotype	IgG
Form	Liquid
Purity	> 95%
Purification	Purified by Protein G.
Storage	Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P02771 (UniProt, ExPASy)
UniProt Secondary AC	B2RBU3
UniProt Entry Name	FETA_HUMAN
Gene Symbol	AFP
GeneID	174
OMIM	104150
KEGG	hsa:174
String	9606.ENSP00000379138
Buffer	0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Alpha Fetoprotein (AFP)

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