Alpha-Methylacyl-CoA Racemase (AMACR) Antibody

AMACR Antibody is a Rabbit Polyclonal antibody against AMACR. This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene.

Target	Alpha-Methylacyl-CoA Racemase (AMACR)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-138 of human AMACR.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9UHK6 (UniProt, ExPASy)
UniProt Entry Name	AMACR_HUMAN
Gene Symbol	AMACR
GeneID	23600
NCBI Accession	NP_055139.4
String	9606.ENSP00000371517
Molecular Weight	Calculated MW: 42 kDa Observed MW: 42/43 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	2.79 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Alpha-Methylacyl-CoA Racemase (AMACR)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue