Muellerian-Inhibiting Factor (AMH) Antibody

Anti Muellerian-Inhibiting Factor (AMH) is a member of the TGF beta superfamily. It is secreted as a homodimeric 140kD disulphide linked precursor that is cleaved to release the mature 30kD homodimer. Originally classified as a foetal testicular hormone that inhibits Anti-Mullerian duct development, AMH is expressed post natally by immature Sertoli cells, and to a lesser degree by granulosa cells. AMH plays a role in testicular differentiation and in the regulation of ovarian follicle growth.

Target	Muellerian-Inhibiting Factor (AMH)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	ELISA, WB, IHC, FCM
Host	Rabbit
Recommended dilutions	WB: 1/1000 - 1/2000, IHC-P: 1/25, FCM: 1/25. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 424-451 amino acids from the Central region of human AMH.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P03971 (UniProt, ExPASy)
UniProt Secondary AC	O75246, Q6GTN3
UniProt Entry Name	MIS_HUMAN
NCBI Accession	NP_000470.2
KEGG	hsa:268
String	9606.ENSP00000221496
Molecular Weight	Calculated MW: 59.2 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Muellerian-Inhibiting Factor (AMH)

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