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Amyloid Oligomers (A11) Antibody (FITC)
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Catalogue No: abx446694
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US$681.50
(Size: 100 µl)
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Datasheet SDS
Amyloid Oligomers (A11) Antibody (FITC) is a Rabbit polyclonal against Amyloid Oligomers (A11). Amyloid monomeric proteins can sometimes oligomerize into destructive amyloid fibrils. Amyloidogenic conformations of non-disease related proteins can be created by partial protein misfolding or denaturation. Many degenerative diseases are known to be related to the accumulation of misfolded proteins as amyloid fibres. These include the amyloid-beta peptide plaques and tau neurofibrillary tangles in senile plaques of Alzheimer's symptomology, the deposition of alpha-synuclein in the Lewy bodies of Parkinson's disease, and accumulation of polyglutamine-containing aggregates in Huntington's disease.
Research Articles on Amyloid Oligomers (A11)
| Target | Amyloid Oligomers (A11) |
| Research Area | Neuroscience, Cell Signaling, Cardiovascular System, Blood, Neurodegeneration, Alzheimer's Disease, Amyloid |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC, IF/ICC, IP |
| Host | Rabbit |
| Recommended dilutions | WB: 1/100, DB: 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | FITC |
| Excitation/Emission | 499/515 |
| Laser Line | 488 |
| Immunogen | Synthetic molecular mimic of soluble oligomers |
| Purification | Purified by Protein A chromatography. |
| Storage | Aliquot and store at 4°C. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P05067 (UniProt, ExPASy) |
| GeneID | 8666 |
| NCBI Accession | NM_000484.2 |
| Buffer | Contains 640.91 mM DMSO, 136.36 mM Ethanolamine, 126.89 mM chlorides, 9.09 mM phosphates, and 9.09 mM NaHCO3. |
| Specificity | Recognizes all types of amyloid oligomers. Appears to recognize a peptide backbone epitope that is common to amyloid oligomers, but is not found in native proteins, amyloidogenic monomer or mature amyloid fibrils. May react with amyloid oligomers from other eukaryotes. |
| Concentration | 0.5 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |