Angiopoietin 2 (Angiopoietin 2) Antibody (Biotin)

Catalogue No: abx105138
Price: £25.00
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Angiopoietin 2 Antibody (Biotin) is a Rabbit Polyclonal antibody against Angiopoietin 2 conjugated to Biotin. Angiopoietin 2 binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. It can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2 mediated loosening of cell matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal.

Target Angiopoietin 2
Reactivity Mouse
Host Rabbit
Clonality Polyclonal
Tested Applications ELISA
Recommended dilutions Optimal dilutions/concentrations should be determined by the end user.
Immunogen Recombinant mouse Angiopoietin-2 protein (19-483AA).
Purity > 95%
Purification Protein G.
Form Liquid
Isotype IgG
Conjugation Biotin
Storage Aliquot and store at -20 °C. Avoid exposure to light. Avoid repeated freeze/thaw cycles.
Swiss Prot O35608
GeneID 11601
Gene Symbol ANGPT2
Buffer 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
UNSPSC Code 12352203
Availability Shipped within 5-10 working days.
Note This product is for research use only.

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