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Angiopoietin 2 (ANGPT2) Antibody (Biotin)

Catalogue No: abx105138
Price: £130.00
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Angiopoietin 2 Antibody (Biotin) is a Rabbit Polyclonal antibody against Angiopoietin 2 conjugated to Biotin. Angiopoietin 2 binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. It can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2 mediated loosening of cell matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal.

Target Angiopoietin 2
Clonality Polyclonal
Reactivity Mouse
Tested Applications ELISA
Host Rabbit
Recommended dilutions Optimal dilutions/concentrations should be determined by the end user.
Conjugation Biotin
Immunogen Recombinant mouse Angiopoietin-2 protein (19-483AA).
Isotype IgG
Form Liquid
Purity > 95%
Purification Protein G.
Storage Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles.
UniProt Primary AC O35608 (UniProt, ExPASy)
UniProt Secondary AC Q3U1A1, Q9D2D2
UniProt Entry Name ANGP2_MOUSE
Gene Symbol ANGPT2
GeneID 11601
KEGG mmu:11601
String 10090.ENSMUSP00000033846
Buffer 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
Concentration 0.25 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Angiopoietin 2 (ANGPT2) Antibody (Biotin)

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