Angiotensin Converting Enzyme 2 (ACE2) Antibody

Angiotensin Converting Enzyme 2 (ACE2) is a Rabbit Polyclonal antibody for the detection of Angiotensin Converting Enzyme 2 (ACE2).

The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63.

Target	Angiotensin Converting Enzyme 2 (ACE2)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	ELISA, IHC
Host	Rabbit
Recommended dilutions	IHC: 1/100 - 1/300. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Synthetic peptide corresponding to human ACE2
Isotype	IgG
Form	Liquid
Purification	Purified by antigen affinity chromatography.
Storage	Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9BYF1 (UniProt, ExPASy)
UniProt Secondary AC	C7ECU1, Q6UWP0, Q86WT0, Q9NRA7, Q9UFZ6
UniProt Entry Name	ACE2_HUMAN
Gene Symbol	ACE2
GeneID	59272
KEGG	hsa:59272
String	9606.ENSP00000389326
Buffer	PBS, pH 7.4, containing 0.05% sodium azide, 50% glycerol.
Concentration	0.33 mg/ml
Availability	Shipped within 5-15 working days.
Note	This product is for research use only.
Directions for use	Centrifuge before opening to ensure complete recovery of vial contents.

Research Articles on Angiotensin Converting Enzyme 2 (ACE2)

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