Angiopoietin-Related Protein 3 (ANGPTL3) Antibody

ANGPTL3 is a member of the angiopoietin-like family of secreted factors. It is predominantly expressed in the liver, and has the characteristic structure of angiopoietins, consisting of a signal peptide, N-terminal coiled-coil domain and the C-terminal fibrinogen (FBN) like domain. The FBN-like domain in angiopoietin-like 3 protein was shown to bind alpha-5/beta-3 integrins, and this binding induced endothelial cell adhesion and migration. This protein may also play a role in the regulation of angiogenesis.

Target	Angiopoietin-Related Protein 3 (ANGPTL3)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 82-114 amino acids from the N-terminal region of human ANGPTL3.
Isotype	IgG
Form	Liquid
Purification	Purified Rabbit Polyclonal Antibody.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9Y5C1 (UniProt, ExPASy)
UniProt Secondary AC	A0JLS0, B1ALJ0, B2RCW1
UniProt Entry Name	ANGL3_HUMAN
String	9606.ENSP00000360170
Molecular Weight	Calculated MW: 53.6 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Angiopoietin-Related Protein 3 (ANGPTL3)

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