Angiopoietin-Related Protein 3 (ANGPTL3) Antibody

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Catalogue No: abx000824
Price: US$203.00
(Size: 20 µl)

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Datasheet SDS
ANGPTL3 Antibody is a Rabbit Polyclonal antibody against ANGPTL3. Angiopoietin-Related Protein 3 (Angptl3) functions as a potent lipoprotein lipase inhibitor and is an important component of plasma triglyceride homeostasis. Angptl3 also plays a role in adipose formation and angiogenesis through its interaction with integrin å(v)beta(3). It is secreted by the liver and is functionally defined by the C-terminal fibrinogen (FBN)-like domain and an N-terminal coiled-coil domain. Angptl3 regulates circulating triglyceride levels during different nutritional states thereby mediating the feeding/fasting cycle. A deficiency of Angptl3 results in abnormally low lipid levels, and a repression of the protein may be protective against atherosclerosis. Angptl3 may also play an important role in hyperlipidemia in diabetes.

Target Angiopoietin-Related Protein 3 (ANGPTL3)
Clonality Polyclonal
Reactivity Mouse
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 231-460 of human ANGPTL3.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q9Y5C1 (UniProt, ExPASy)
UniProt Secondary AC A0JLS0, B1ALJ0, B2RCW1
UniProt Entry Name ANGL3_HUMAN
Gene Symbol ANGPTL3
GeneID 27329
NCBI Accession NP_055310.1
String 9606.ENSP00000360170
Molecular Weight Calculated MW: 54 kDa
Observed MW: 53 kDa
Buffer PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration > 0.2 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Angiopoietin-Related Protein 3 (ANGPTL3)


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