Angiopoietin Like Protein 3 (ANGPTL3) Antibody

Catalogue No: abx000824
Price: £120.00
(Size: 20 µl)
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ANGPTL3 Antibody is a Rabbit Polyclonal antibody against ANGPTL3. Angiopoietin-like protein 3 (Angptl3) functions as a potent lipoprotein lipase inhibitor and is an important component of plasma triglyceride homeostasis. Angptl3 also plays a role in adipose formation and angiogenesis through its interaction with integrin å(v)beta(3). It is secreted by the liver and is functionally defined by the C-terminal fibrinogen (FBN)-like domain and an N-terminal coiled-coil domain. Angptl3 regulates circulating triglyceride levels during different nutritional states thereby mediating the feeding/fasting cycle. A deficiency of Angptl3 results in abnormally low lipid levels, and a repression of the protein may be protective against atherosclerosis. Angptl3 may also play an important role in hyperlipidemia in diabetes.

Target ANGPTL3
Clonality Polyclonal
Reactivity Mouse
Tested Applications WB, IHC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human ANGPTL3.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q9Y5C1 (UniProt, ExPASy)
UniProt Secondary AC A0JLS0, B1ALJ0, B2RCW1
UniProt Entry Name ANGL3_HUMAN
Gene Symbol ANGPTL3
GeneID 27329
String 9606.ENSP00000360170
Molecular Weight Calculated MW: 53 kDa
Observed MW: 53 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 0.5 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on ANGPTL3

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