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Angiopoietin-Related Protein 3 (ANGPTL3) Antibody
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Catalogue No: abx000824
Price:
US$217.50
(Size: 20 µl)
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ANGPTL3 Antibody is a Rabbit Polyclonal antibody against ANGPTL3. Angiopoietin-Related Protein 3 (Angptl3) functions as a potent lipoprotein lipase inhibitor and is an important component of plasma triglyceride homeostasis. Angptl3 also plays a role in adipose formation and angiogenesis through its interaction with integrin å(v)beta(3). It is secreted by the liver and is functionally defined by the C-terminal fibrinogen (FBN)-like domain and an N-terminal coiled-coil domain. Angptl3 regulates circulating triglyceride levels during different nutritional states thereby mediating the feeding/fasting cycle. A deficiency of Angptl3 results in abnormally low lipid levels, and a repression of the protein may be protective against atherosclerosis. Angptl3 may also play an important role in hyperlipidemia in diabetes.
Research Articles on Angiopoietin-Related Protein 3 (ANGPTL3)
| Target | Angiopoietin-Related Protein 3 (ANGPTL3) |
| Clonality | Polyclonal |
| Reactivity | Mouse |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant protein corresponding to ANGPTL3. The exact sequence is proprietary. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9Y5C1 (UniProt, ExPASy) |
| UniProt Secondary AC | A0JLS0, B1ALJ0, B2RCW1 |
| UniProt Entry Name | ANGL3_HUMAN |
| Gene Symbol | ANGPTL3 |
| GeneID | 27329 |
| NCBI Accession | NP_055310.1 |
| String | 9606.ENSP00000360170 |
| Molecular Weight | Calculated MW: 54 kDa Observed MW: 53 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |