AP-3 Complex Subunit Mu-1 (AP3M1) Antibody

The protein encoded by this gene is the medium subunit of AP-3, which is an adaptor-related protein complex associated with the Golgi region as well as more peripheral intracellular structures. AP-3 facilitates the budding of vesicles from the Golgi membrane and may be directly involved in protein sorting to the endosomal/lysosomal system. AP-3 is a heterotetrameric protein complex composed of two large subunits (delta and beta3), a medium subunit (mu3), and a small subunit (sigma 3). Mutations in one of the large subunits of AP-3 have been associated with the Hermansky-Pudlak syndrome, a genetic disorder characterized by defective lysosome-related organelles. Alternatively spliced transcript variants encoding the same protein have been observed.

Target	AP-3 Complex Subunit Mu-1 (AP3M1)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 390-418 amino acids from the C-terminal region of human AP3M1.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9Y2T2 (UniProt, ExPASy)
UniProt Secondary AC	Q5JQ12, Q9H5L2
UniProt Entry Name	AP3M1_HUMAN
Gene Symbol	AP3M1
String	9606.ENSP00000347408
Molecular Weight	Calculated MW: 46.9 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse and Cow AP3M1.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on AP-3 Complex Subunit Mu-1 (AP3M1)

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