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Amyloid-Beta A4 Precursor Protein-Binding Family B Member 1 (APBB1) Antibody

Catalogue No: abx001587
Price: £120.00
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Amyloid-Beta A4 Precursor Protein-Binding Family B Member 1 (APBB1) Antibody Amyloid-Beta A4 Precursor Protein-Binding Family B Member 1 (APBB1) Antibody Amyloid-Beta A4 Precursor Protein-Binding Family B Member 1 (APBB1) Antibody

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APBB1 Antibody is a Rabbit Polyclonal antibody against APBB1. The protein encoded by this gene is a member of the Fe65 protein family. It is an adaptor protein localized in the nucleus. It interacts with the Alzheimer's disease amyloid precursor protein (APP), transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein. APP functions as a cytosolic anchoring site that can prevent the gene product's nuclear translocation. This encoded protein could play an important role in the pathogenesis of Alzheimer's disease. It is thought to regulate transcription. Also it is observed to block cell cycle progression by downregulating thymidylate synthase expression. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Target APBB1
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human APBB1.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC O00213 (UniProt, ExPASy)
UniProt Entry Name APBB1_HUMAN
Gene Symbol APBB1
GeneID 322
KEGG hsa:322
String 9606.ENSP00000477213
Molecular Weight Calculated MW: 49 kDa, 52 kDa, 53 kDa, 54 kDa, 76 kDa, 77 kDa
Observed MW: 63 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Amyloid-Beta A4 Precursor Protein-Binding Family B Member 1 (APBB1) Antibody

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