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DNA-(Apurinic Or Apyrimidinic Site) Lyase (APEX1) Antibody

Catalogue No: abx001032
Price: £120.00
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DNA-(Apurinic Or Apyrimidinic Site) Lyase (APEX1) Antibody DNA-(Apurinic Or Apyrimidinic Site) Lyase (APEX1) Antibody DNA-(Apurinic Or Apyrimidinic Site) Lyase (APEX1) Antibody DNA-(Apurinic Or Apyrimidinic Site) Lyase (APEX1) Antibody

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APEX1 Antibody is a Rabbit Polyclonal antibody against APEX1. Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein.

Target APEX1
Clonality Polyclonal
Reactivity Human
Tested Applications WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/100, IF/ICC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human APEX1.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P27695 (UniProt, ExPASy)
UniProt Secondary AC Q969L5, Q99775
UniProt Entry Name APEX1_HUMAN
Gene Symbol APEX1
GeneID 318
KEGG hsa:328
String 9606.ENSP00000216714
Molecular Weight Calculated MW: 35 kDa
Observed MW: 39 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on DNA-(Apurinic Or Apyrimidinic Site) Lyase (APEX1) Antibody

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