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Amyloid Beta Precursor Like Protein 2 (APLP2) Antibody
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Catalogue No: abx004176
Price:
US$348.00
(Size: 60 µl)
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APLP2 Antibody is a Rabbit Polyclonal antibody against APLP2. This gene encodes amyloid precursor- like protein 2 (APLP2), which is a member of the APP (amyloid precursor protein) family including APP, APLP1 and APLP2. This protein is ubiquitously expressed. It contains heparin-, copper- and zinc- binding domains at the N-terminus, BPTI/Kunitz inhibitor and E2 domains in the middle region, and transmembrane and intracellular domains at the C-terminus. This protein interacts with major histocompatibility complex (MHC) class I molecules. The synergy of this protein and the APP is required to mediate neuromuscular transmission, spatial learning and synaptic plasticity. This protein has been implicated in the pathogenesis of Alzheimer's disease. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Research Articles on Amyloid Beta Precursor Like Protein 2 (APLP2)
| Target | Amyloid Beta Precursor Like Protein 2 (APLP2) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human APLP2 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q06481 (UniProt, ExPASy) |
| UniProt Entry Name | APLP2_HUMAN |
| Gene Symbol | APLP2 |
| GeneID | 334 |
| NCBI Accession | NP_001633.1 |
| KEGG | hsa:334 |
| String | 9606.ENSP00000263574 |
| Molecular Weight | Calculated MW: 59 kDa/79 kDa/80 kDa/85 kDa/86 kDa/87 kDa Observed MW: 87 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
