Apolipoprotein A1 (APOA1) Antibody
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Catalogue No: abx010413
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US$427.75
(Size: 100 µl)
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Datasheet SDS
APOA1: apolipoprotein A-I, it is the major protein component of high density lipoprotein (HDL) in plasma. The protein promotes cholesterol efflux from tissues to the liver for excretion, and it is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. Defects in the Apolipoprotein A I gene are associated with HDL deficiency and Tangier disease. The therapeutic potential of apoA-I has been recently assessed in patients with acute coronary syndromes, using a recombinant form of a naturally occurring variant of apoA-I. The availability of recombinant normal apoA-I should facilitate further investigation into the potential usefulness of apoA-I in preventing atherosclerotic vascular diseases.
Research Articles on Apolipoprotein A1 (APOA1)
| Target | Apolipoprotein A1 (APOA1) |
| Research Area | Signal Transduction, Neuroscience, Cancer, Epigenetics And Nuclear Signaling |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human APOA1 expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P02647 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K866, Q6LDN9, Q6Q785, Q9UCS8, Q9UCT8 |
| UniProt Entry Name | APOA1_HUMAN |
| Gene Symbol | APOA1 |
| GeneID | 335 |
| OMIM | 105200 |
| NCBI Accession | NP_000030.1 |
| HGNC | 600 |
| KEGG | hsa:335 |
| Ensembl | ENSG00000118137 |
| String | 9606.ENSP00000236850 |
| Molecular Weight | 25 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |