Apolipoprotein A-V (APOA5) Antibody

Apolipoprotein A5 (ApoA5) is fast gaining attention as a key regulator of serum triglyceride concentrations. An ApoA5 mouse knock-out model produced an approximately four fold increase in serum triglycerides, whereas a knock-in model with human ApoA5 produced 50–70% lower concentrations of mouse serum triglycerides. In addition, peroxisome proliferator-activated receptor- agonists, which are used clinically to lower serum triglyceride concentrations, cause increased ApoA5 mRNA expression. Despite these compelling molecular biology data, relatively little is known about ApoA5 protein in human serum. This antibody pair detected recombinant apoa5 protein in sandwich ELISA format and could be potential reagents for the development of clinical diagnostic kits.

Target	Apolipoprotein A-V (APOA5)
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA, IF/ICC
Host	Mouse
Recommended dilutions	ELISA: 1/10000, IF/ICC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Purified recombinant fragment of human Apoa5 expressed in E. coli.
Isotype	IgG1
Form	Liquid
Purification	Unpurified ascites.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q6Q788 (UniProt, ExPASy)
UniProt Secondary AC	B0YIV9, Q3MIK6, Q6UWK9, Q9UBJ3
UniProt Entry Name	APOA5_HUMAN
Gene Symbol	APOA5
GeneID	116519
OMIM	144650
HGNC	17288
KEGG	hsa:116519
Ensembl	ENSG00000110243
String	9606.ENSP00000445002
Molecular Weight	41 kDa
Buffer	Ascitic fluid containing 0.03% sodium azide.
Concentration	Not determined.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Apolipoprotein A-V (APOA5)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue