Apolipoprotein B (APOB) Antibody

APOB Antibody is a Rabbit Polyclonal antibody against APOB. APOB, also named as Apo B-48 and Apo B-100, is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). APOB functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor. Defects in APOB are a cause of familial hypobetalipoproteinemia (FHBL). Defects in APOB are a cause of familial ligand-defective apolipoprotein B-100 (FDB). Defects in APOB associated with defects in other genes (polygenic) can contribute to hypocholesterolemia. The antibody is specific to APOB.

Target	Apolipoprotein B (APOB)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 28-330 of human ApoB.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P04114 (UniProt, ExPASy)
UniProt Entry Name	APOB_HUMAN
Gene Symbol	APOB
GeneID	338
NCBI Accession	NP_000375.3
KEGG	hsa:338
String	9606.ENSP00000233242
Molecular Weight	Calculated MW: 516 kDa Observed MW: 250 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Apolipoprotein B (APOB)

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