Apolipoprotein B (APOB) Antibody
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Catalogue No: abx001189
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US$217.50
(Size: 20 µl)
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Datasheet SDS
APOB Antibody is a Rabbit Polyclonal antibody against APOB. APOB, also named as Apo B-48 and Apo B-100, is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). APOB functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor. Defects in APOB are a cause of familial hypobetalipoproteinemia (FHBL). Defects in APOB are a cause of familial ligand-defective apolipoprotein B-100 (FDB). Defects in APOB associated with defects in other genes (polygenic) can contribute to hypocholesterolemia. The antibody is specific to APOB.
Research Articles on Apolipoprotein B (APOB)
| Target | Apolipoprotein B (APOB) |
| Research Area | Metabolism, Endocrinology, Cardiovascular Biology, Hepatology, Nutrition |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/1000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant protein corresponding to APOB. The exact sequence is proprietary. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P04114 (UniProt, ExPASy) |
| UniProt Entry Name | APOB_HUMAN |
| Gene Symbol | APOB |
| GeneID | 338 |
| NCBI Accession | NP_000375.3 |
| KEGG | hsa:338 |
| String | 9606.ENSP00000233242 |
| Molecular Weight | Calculated MW: 516 kDa Observed MW: 250 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |