Apoptosis Protease Activating Factor 1 (APAF1) Antibody

Catalogue No: abx000846
Price: £120.00
(Size: 20 µl)
Reviews: 0 reviews
(0 reviews)

Click on the image to see the image legend

Apoptosis Protease Activating Factor 1 (APAF1) Antibody

Available Options

* Size:




APAF1 Antibody is a Rabbit Polyclonal antibody against APAF1. This gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].

Target APAF1
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC, IP
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IP: 1/20 - 1/50. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human APAF1.
Isotype IgG
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC O14727 (UniProt, ExPASy)
GeneID 317
Molecular Weight 142 kDa
Buffer PBS with 0.02% sodium azide, 50% glycerol, pH 7.3.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Apoptosis Protease Activating Factor 1 (APAF1) Antibody

Write a review

Your Name
Your Email Address
PMID
DOI
Type
Your Review

Note: HTML is not translated!

Rating Bad Good


Tags:
(Click to show)