Amyloid-beta Precursor Protein Phospho-Thr743 (APP pT743) Antibody

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Catalogue No: abx000096
Price: US$232.00
(Size: 20 µl)

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Amyloid-beta Precursor Protein Phospho-Thr743 (APP pT743) Antibody Amyloid-beta Precursor Protein Phospho-Thr743 (APP pT743) Antibody

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Datasheet SDS
APP (pT743) Antibody is a Rabbit Polyclonal antibody against APP (pT743). This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.

Target Amyloid-beta Precursor Protein Phospho-Thr743 (APP pT743)
Clonality Polyclonal
Reactivity Mouse, Rat
Tested Applications ELISA, WB
Host Rabbit
Recommended dilutions ELISA: 1 µg/ml, WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Synthetic peptide corresponding to APP pT743. The exact sequence is proprietary.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P05067 (UniProt, ExPASy)
Gene Symbol APP
GeneID 4609
NCBI Accession NP_958817.1
Molecular Weight Calculated MW: 87 kDa
Observed MW: 87 kDa
Buffer PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration > 0.2 mg/ml
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Amyloid-beta Precursor Protein Phospho-Thr743 (APP pT743)


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