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Adenine Phosphoribosyltransferase (APRT) Antibody
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Catalogue No: abx031776
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US$326.25
(Size: 80 µl)
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Datasheet SDS
A conserved feature of APRT is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2, 8-dihydroxyadenine urolithiasis.
Research Articles on Adenine Phosphoribosyltransferase (APRT)
| Target | Adenine Phosphoribosyltransferase (APRT) |
| Research Area | Enzymes and Kinases, Metabolism, Kidney Biomarkers |
| Clonality | Polyclonal |
| Reactivity | Human, Rat |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 143-170 amino acids from the C-terminal region of human APRT. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P07741 (UniProt, ExPASy) |
| UniProt Secondary AC | G5E9J2, Q3KP55, Q68DF9 |
| UniProt Entry Name | APT_HUMAN |
| NCBI Accession | NP_000476.1 NP_001025189.1 |
| KEGG | hsa:353 |
| String | 9606.ENSP00000367615 |
| Molecular Weight | Calculated MW: 19.6 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |