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Amphiregulin (AREG) Antibody

Catalogue No: abx001536
Price: £120.00
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Amphiregulin (AREG) Antibody

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AREG Antibody is a Rabbit Polyclonal antibody against AREG. Amphiregulin (AREG) is one of the ligands of the epidermal growth factor receptor (EGFR). AREG plays a central role in mammary gland development and branching morphogenesis in organs and is expressed both in physiological and in cancerous tissues. The AREG protein is synthesized as a 252-amino acid transmembrane precursor, pro-AREG. At the plasma membrane, pro-AREG is subjected to sequential proteolytic cleavages within its ectodomain and is then released as the soluble AREG protein. Depending on the cell type and microenvironment, AREG can be produced in multiple cellular and mature forms using alternative pro-AREG cleavage sites and glycosylation motifs.

Target AREG
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human AREG.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P15514 (UniProt, ExPASy)
UniProt Secondary AC Q5U026
UniProt Entry Name AREG_HUMAN
Gene Symbol AREG
GeneID 374
KEGG hsa:374
String 9606.ENSP00000379097
Molecular Weight Calculated MW: 27 kDa
Observed MW: 35 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Amphiregulin (AREG) Antibody

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