Rho GDP-Dissociation Inhibitor 2 (ARHGDIB) Antibody

ARHGDIB Antibody is a Rabbit Polyclonal antibody against ARHGDIB. Members of the Rho (or ARH) protein family (see MIM 165390) and other Ras-related small GTP-binding proteins (see MIM 179520) are involved in diverse cellular events, including cell signaling, proliferation, cytoskeletal organization, and secretion. The GTP-binding proteins are active only in the GTP-bound state. At least 3 classes of proteins tightly regulate cycling between the GTP-bound and GDP-bound states: GTPase-activating proteins (GAPs), guanine nucleotide-releasing factors (GRFs), and GDP-dissociation inhibitors (GDIs). The GDIs, including ARHGDIB, decrease the rate of GDP dissociation from Ras-like GTPases (summary by Scherle et al., 1993.

Target	Rho GDP-Dissociation Inhibitor 2 (ARHGDIB)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-201 of human ARHGDIB.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P52566 (UniProt, ExPASy)
UniProt Secondary AC	B5BU79
UniProt Entry Name	GDIR2_HUMAN
Gene Symbol	ARHGDIB
GeneID	397
NCBI Accession	NP_001166.3
KEGG	hsa:397
String	9606.ENSP00000228945
Molecular Weight	Calculated MW: 23 kDa Observed MW: 23 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Rho GDP-Dissociation Inhibitor 2 (ARHGDIB)

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