Rho Guanine Nucleotide Exchange Factor 18 (ARHGEF18) Antibody
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Catalogue No: abx029859
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US$326.25
(Size: 80 µl)
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Datasheet SDS
Rho GTPases are GTP binding proteins that regulate a wide spectrum of cellular functions. These cellular processes include cytoskeletal rearrangements, gene transcription, cell growth and motility. Activation of Rho GTPases is under the direct control of guanine nucleotide exchange factors (GEFs). The protein encoded by this gene is a guanine nucleotide exchange factor and belongs to the Rho GTPase GFE family. Family members share a common feature, a Dbl (DH) homology domain followed by a pleckstrin (PH) homology domain. Alternatively spliced transcript variants encoding different isoforms have been identified.
Research Articles on Rho Guanine Nucleotide Exchange Factor 18 (ARHGEF18)
| Target | Rho Guanine Nucleotide Exchange Factor 18 (ARHGEF18) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 91-119 amino acids from the N-terminal region of human ARHGEF18. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q6ZSZ5 (UniProt, ExPASy) |
| UniProt Secondary AC | A8MV62, B5ME81, I3L1I5, O60274, Q6DD92 |
| UniProt Entry Name | ARHGI_HUMAN |
| Gene Symbol | ARHGEF18 |
| KEGG | hsa:23370 |
| String | 9606.ENSP00000352995 |
| Molecular Weight | Calculated MW: 152 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |