Rho Guanine Nucleotide Exchange Factor 7 (ARHGEF7) Antibody

Catalogue No: abx001025
Price: £120.00
(Size: 20 µl)
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ARHGEF7 Antibody is a Rabbit Polyclonal antibody against ARHGEF7. Rho GTPases play a fundamental role in numerous cellular processes triggered by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It forms a complex with the small GTP binding protein Rac1 and recruits Rac1 to membrane ruffles and to focal adhesions. This protein can induce membrane ruffling. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Target ARHGEF7
Clonality Polyclonal
Reactivity Human, Mouse, Monkey
Tested Applications WB, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human ARHGEF7.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q14155 (UniProt, ExPASy)
UniProt Entry Name ARHG7_HUMAN
Gene Symbol ARHGEF7
GeneID 8874
KEGG hsa:8874
String 9606.ENSP00000364893
Molecular Weight Calculated MW: 70 kDa, 73 kDa, 82 kDa, 84 kDa, 87 kDa, 90 kDa
Observed MW: 86 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 0.5 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on ARHGEF7

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