Rho Guanine Nucleotide Exchange Factor 7 (ARHGEF7) Antibody

ARHGEF7 Antibody is a Rabbit Polyclonal antibody against ARHGEF7. Rho GTPases play a fundamental role in numerous cellular processes triggered by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It forms a complex with the small GTP binding protein Rac1 and recruits Rac1 to membrane ruffles and to focal adhesions. This protein can induce membrane ruffling. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Target	Rho Guanine Nucleotide Exchange Factor 7 (ARHGEF7)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human ARHGEF7.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q14155 (UniProt, ExPASy)
UniProt Entry Name	ARHG7_HUMAN
Gene Symbol	ARHGEF7
GeneID	8874
NCBI Accession	NP_001106984.1
KEGG	hsa:8874
String	9606.ENSP00000364893
Molecular Weight	Calculated MW: 90 kDa Observed MW: 86 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Rho Guanine Nucleotide Exchange Factor 7 (ARHGEF7)

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