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Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT) Antibody
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Catalogue No: abx000925
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US$217.50
(Size: 20 µl)
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Datasheet SDS
ARNT Antibody is a Rabbit Polyclonal antibody against ARNT. This gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias. Alternative splicing results in multiple transcript variants.
Research Articles on Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT)
| Target | Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT) |
| Research Area | Signal Transduction |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 420-485 of human HIF1β/ARNT. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P27540 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R9H1, C4AMA1, F8WAP6, Q59ED4, Q5QP39, Q8NDC7 |
| UniProt Entry Name | ARNT_HUMAN |
| Gene Symbol | ARNT |
| GeneID | 405 |
| NCBI Accession | NP_001659.1 |
| KEGG | hsa:405 |
| String | 9606.ENSP00000351407 |
| Molecular Weight | Calculated MW: 87 kDa Observed MW: 87 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
