Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT) Antibody

ARNT Antibody is a Rabbit Polyclonal antibody against ARNT. This gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias. Alternative splicing results in multiple transcript variants.

Target	Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 420-485 of human HIF1β/ARNT.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P27540 (UniProt, ExPASy)
UniProt Secondary AC	B2R9H1, C4AMA1, F8WAP6, Q59ED4, Q5QP39, Q8NDC7
UniProt Entry Name	ARNT_HUMAN
Gene Symbol	ARNT
GeneID	405
NCBI Accession	NP_001659.1
KEGG	hsa:405
String	9606.ENSP00000351407
Molecular Weight	Calculated MW: 87 kDa Observed MW: 87 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT)

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