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Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT) Antibody

Catalogue No: abx000925
Price: £120.00
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ARNT Antibody is a Rabbit Polyclonal antibody against ARNT. This gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias. Alternative splicing results in multiple transcript variants.

Target ARNT
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human ARNT.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P27540 (UniProt, ExPASy)
UniProt Secondary AC B2R9H1, C4AMA1, F8WAP6, Q59ED4, Q5QP39, Q8NDC7
UniProt Entry Name ARNT_HUMAN
Gene Symbol ARNT
GeneID 405
String 9606.ENSP00000351407
Molecular Weight Calculated MW: 84 kDa, 85 kDa, 86 kDa
Observed MW: 87 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT) Antibody

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