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Arrestin Beta 1 (ARRB1) Antibody

Catalogue No: abx000951
Price: £120.00
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Arrestin Beta 1 (ARRB1) Antibody

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ARRB1 Antibody is a Rabbit Polyclonal antibody against ARRB1. Members of ARRB1/beta-ARRB1 protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. ARRB1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-ARRB1 system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of ARRB1 have been described.

Target ARRB1
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IF/ICC: 1/20 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human ARRB1.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P49407 (UniProt, ExPASy)
UniProt Secondary AC B6V9G8, O75625, O75630, Q2PP20, Q9BTK8
UniProt Entry Name ARRB1_HUMAN
Gene Symbol ARRB1
GeneID 408
KEGG hsa:40
String 9606.ENSP00000409581
Molecular Weight Calculated MW: 46 kDa, 47 kDa
Observed MW: 56 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Arrestin Beta 1 (ARRB1) Antibody

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