Ankyrin Repeat And SOCS Box Containing 2 (ASB2) Antibody

The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. This gene is induced by all-trans retinoic acid. In myeloid leukemia cells, the expression of this encoded protein has been shown to induce growth inhibition and chromatin condensation. Multiple alternatively spliced transcript variants have been described for this gene but their full length sequences are not known.

Target	Ankyrin Repeat And SOCS Box Containing 2 (ASB2)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 58-86 amino acids from the N-terminal region of human ASB2.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles.
Shelf Life	12 months.
UniProt Primary AC	Q96Q27 (UniProt, ExPASy)
UniProt Secondary AC	B2RDP9, B4E166, Q9NSU5, Q9Y567
UniProt Entry Name	ASB2_HUMAN
Gene Symbol	ASB2
KEGG	hsa:51676
String	9606.ENSP00000451575
Molecular Weight	Calculated MW: 70.2 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Research Articles on Ankyrin Repeat And SOCS Box Containing 2 (ASB2)

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