Achaete-Scute Homolog 1 (ASCL1) Antibody
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Catalogue No: abx031181
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US$326.25
(Size: 80 µl)
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Datasheet SDS
This gene encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases.
Research Articles on Achaete-Scute Homolog 1 (ASCL1)
| Target | Achaete-Scute Homolog 1 (ASCL1) |
| Research Area | Tumor Immunity, Cancer |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 63-90 amino acids from the N-terminal region of human ASCL1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P50553 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K3C4, Q9BQ30 |
| UniProt Entry Name | ASCL1_HUMAN |
| NCBI Accession | NP_004307.2 |
| KEGG | hsa:429 |
| String | 9606.ENSP00000266744 |
| Molecular Weight | Calculated MW: 25.5 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |