Agouti-Signaling Protein (ASIP) Antibody
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Catalogue No: abx005235
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US$348.00
(Size: 60 µl)
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Datasheet SDS
ASIP Antibody is a Rabbit Polyclonal antibody against ASIP. In mice, the agouti gene encodes a paracrine signaling molecule that causes hair follicle melanocytes to synthesize pheomelanin, a yellow pigment, instead of the black or brown pigment, eumelanin. Pleiotropic effects of constitutive expression of the mouse gene include adult-onset obesity, increased tumor susceptibility, and premature infertility. This gene is highly similar to the mouse gene and encodes a secreted protein that may affect the quality of hair pigmentation, act as a pharmacological antagonist of alpha-melanocyte-stimulating hormone, play a role in neuroendocrine aspects of melanocortin action, and have a functional role in regulating lipid metabolism in adipocytes.
Research Articles on Agouti-Signaling Protein (ASIP)
| Target | Agouti-Signaling Protein (ASIP) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | IF/ICC |
| Host | Rabbit |
| Recommended dilutions | IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human ASIP |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P42127 (UniProt, ExPASy) |
| UniProt Secondary AC | Q3SXL2 |
| UniProt Entry Name | ASIP_HUMAN |
| Gene Symbol | ASIP |
| GeneID | 434 |
| NCBI Accession | NP_001663.2 |
| KEGG | hsa:434 |
| String | 9606.ENSP00000454804 |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-7 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
