(Size: 20 µl)
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ATF2 Antibody is a Rabbit Polyclonal antibody against ATF2. This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cell's DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for this gene
Research Articles on Cyclic AMP-Dependent Transcription Factor ATF-2 (ATF2) Antibody
||WB, IHC, IF/ICC
||WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
||Recombinant protein of human ATF2.
||Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
|UniProt Primary AC
||Calculated MW: 13-15 kDa, 23-24 kDa, 35-54 kDa
Observed MW: 70 kDa
||PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
||> 1 mg/ml
||Shipped within 5-10 working days.
||This product is for research use only.