ATF4 Antibody

Catalogue No: abx000590
Price: $56.00
Reviews: 0 reviews
(0 reviews)

Click on the image to see the image legend

ATF4 Antibody
ATF4 Antibody ATF4 Antibody ATF4 Antibody ATF4 Antibody

Available Options

* Size:




ATF4 Antibody is a Rabbit Polyclonal antibody against ATF4. ATF4 is a transcription factor, that accumulates predominantly in osteoblasts, where it regulates terminal osteoblast differentiation and bone formation. As a basic leucine-zipper (bZip) transcription factor, ATF4 can regulate amino acid metabolism, cellular redox state, and anti-stress responses. It also regulates age-related and diet-induced obesity and glucose homeostasis in mammals, and has conserved metabolic functions in flies. Due to its location at chromosome 22q13, a region linked to schizophrenia, ATF4 is considered as a positional candidate gene for schizophrenia. Otherwise, since ATF4 is induced by tumour microenvironmental factors, and regulates processes relevant to cancer progression, it might serve as a potential therapeutic target in cancer. This antibody is a rabbit polyclonal antibody raised against full length human ATF4 antigen.

Target ATF4
Reactivity Human, Mouse, Rat
Origin Human
Host Rabbit
Clonality Polyclonal
Tested Applications WB
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Immunogen Recombinant protein of human ATF4.
Purification Affinity purified.
Isotype IgG
Conjugation Unconjugated
Storage Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Molecular Weight 39 kDa
Swiss Prot P18848
GeneID 468
Gene Symbol ATF4
Concentration 1.67 mg/ml
Buffer PBS with 0.02% sodium azide, 50% glycerol, pH 7.3.
Availability Shipped within 5-10 working days.
Note This product is for research use only.

Write a review

Your Name
Your Review
Note: HTML is not translated!

Rating Bad Good


Tags:
(Click to show)