Autophagy-Related Protein 16-1 (ATG16L1) Antibody

ATG16L1 Antibody is a Rabbit Polyclonal antibody against ATG16L1. The protein encoded by this gene is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in this gene are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10). Several transcript variants encoding different isoforms have been found for this gene.

Target	Autophagy-Related Protein 16-1 (ATG16L1)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 90-300 of human ATG16L1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q676U5 (UniProt, ExPASy)
UniProt Entry Name	A16L1_HUMAN
Gene Symbol	ATG16L1
GeneID	55054
NCBI Accession	NP_110430.5
KEGG	hsa:55054
String	9606.ENSP00000375872
Molecular Weight	Calculated MW: 68 kDa Observed MW: 66/68 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Autophagy-Related Protein 16-1 (ATG16L1)

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