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ATM (pS1981) Antibody

Catalogue No: abx000098
Price: £120.00
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ATM (pS1981) Antibody ATM (pS1981) Antibody ATM (pS1981) Antibody ATM (pS1981) Antibody

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ATM (pS1981) Antibody is a Rabbit Polyclonal antibody against ATM (pS1981). The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder.

Target ATM (pS1981)
Clonality Polyclonal
Reactivity Human
Tested Applications WB, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding S1981 of human ATM.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q13315 (UniProt, ExPASy)
UniProt Secondary AC B2RNX5, O15429, Q12758, Q16551, Q93007, Q9NP02, Q9UCX7
UniProt Entry Name ATM_HUMAN
Gene Symbol ATM
GeneID 472
KEGG hsa:472
String 9606.ENSP00000278616
Molecular Weight Calculated MW: 350 kDa
Observed MW: 350 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on ATM (pS1981) Antibody

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