ATPase, Na+/K+ Transporting Beta 2 Polypeptide (ATP1B2) Antibody

The protein belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ ATPases. Na+/K+ ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane.

Target	ATPase, Na+/K+ Transporting Beta 2 Polypeptide (ATP1B2)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC, FCM
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/50 - 1/100, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 115-141 amino acids from the Central region of human ATP1B2.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P14415 (UniProt, ExPASy)
UniProt Secondary AC	A0AV17, A8K278, D3DTQ2, O60444
UniProt Entry Name	AT1B2_HUMAN
KEGG	hsa:482
String	9606.ENSP00000250111
Molecular Weight	Calculated MW: 33.4 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse, Rat, Cow and Rabbit ATP1B2.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on ATPase, Na+/K+ Transporting Beta 2 Polypeptide (ATP1B2)

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