ATPase, Ca++ Transporting, Cardiac Muscle, Slow Twitch 2 (ATP2A2) Antibody
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Catalogue No: abx029222
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US$326.25
(Size: 80 µl)
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Datasheet SDS
This gene encodes one of the SERCA Ca (2+) ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol into the sarcoplasmic reticulum lumen, and is involved in regulation of the contraction/relaxation cycle. Mutations in this gene cause Darier-White disease, also known as keratosis follicularis, an autosomal dominant skin disorder characterized by loss of adhesion between epidermal cells and abnormal keratinization. Alternative splicing results in multiple transcript variants encoding different isoforms.
Research Articles on ATPase, Ca++ Transporting, Cardiac Muscle, Slow Twitch 2 (ATP2A2)
| Target | ATPase, Ca++ Transporting, Cardiac Muscle, Slow Twitch 2 (ATP2A2) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 374-403 amino acids from the Central region of human ATP2A2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P16615 (UniProt, ExPASy) |
| UniProt Secondary AC | A6NDN7, B4DF05, P16614, Q86VJ2 |
| UniProt Entry Name | AT2A2_HUMAN |
| Gene Symbol | ATP2A2 |
| KEGG | hsa:488 |
| String | 9606.ENSP00000440045 |
| Molecular Weight | Calculated MW: 115 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |