ATPase, Ca++ Transporting, Cardiac Muscle, Slow Twitch 2 (ATP2A2) Antibody

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Catalogue No: abx001018
Price: US$203.00
(Size: 20 µl)

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Datasheet SDS
ATP2A2 Antibody is a Rabbit Polyclonal antibody against ATP2A2. This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol into the sarcoplasmic reticulum lumen, and is involved in regulation of the contraction/relaxation cycle. Mutations in this gene cause Darier-White disease, also known as keratosis follicularis, an autosomal dominant skin disorder characterized by loss of adhesion between epidermal cells and abnormal keratinization. Alternative splicing results in multiple transcript variants encoding different isoforms.

Target ATPase, Ca++ Transporting, Cardiac Muscle, Slow Twitch 2 (ATP2A2)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/2000 - 1/10000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein containing a sequence within amino acids 1-80 of human SERCA2/ATP2A2.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P16615 (UniProt, ExPASy)
UniProt Secondary AC A6NDN7, B4DF05, P16614, Q86VJ2
UniProt Entry Name AT2A2_HUMAN
Gene Symbol ATP2A2
GeneID 488
NCBI Accession NP_733765.1
KEGG hsa:488
String 9606.ENSP00000440045
Molecular Weight Calculated MW: 115 kDa
Observed MW: 115 kDa
Buffer PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration > 0.2 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on ATPase, Ca++ Transporting, Cardiac Muscle, Slow Twitch 2 (ATP2A2)


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